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April 21, 2008 – 10:41 pm

According to the prescribing information, MEVACOR should not be used by anyone allergic to any of its components, people with liver disease, or by women who are pregnant, breast-feeding or likely to become pregnant. It is recommended that liver function tests be performed in all patients prior to daily use of MEVACOR 40 mg or more.

Muscle pain or weakness in patients taking prescription MEVACOR should be reported to a doctor because these could be signs of a serious side effect. Patients should tell their doctors about other medications they are taking in order to avoid possible drug interactions.

The most common adverse events reported with MEVACOR 20 mg taken once a day were diarrhea, flatulence, headache and myalgia.

Nicorette, NicoDerm CQ and alli trademarks are either owned by and/or licensed to GSK or associated companies. Xenical is a registered trademark of the Roche Group.

OTC MEVACOR would be marketed in the United States by GSK Consumer Healthcare, a GSK division with a well-established record of bringing informed access to OTC medicines.

In 1996, GSK Consumer Healthcare launched the first OTC nicotine replacement therapies, Nicorette and NicoDerm CQ, together with an innovative Committed Quitters behavioral support program. Through increased access to GSK’s smoking cessation brands and support, more than five million adults in the United States have quit smoking.

In 2004, GSK Consumer Healthcare acquired the OTC marketing rights to orlistat in the United States from the Roche Group (orlistat 120 mg is marketed as the prescription product Xenical(R) by Roche). In June 2007, GSK Consumer Healthcare launched alli in the United States, the first FDA-approved OTC weight control medicine. alli (orlistat 60mg) provides overweight adults a proven weight loss medicine and a comprehensive, tailored, behavioral support program.

The study authors, led by Marion J. Franz, a registered dietitian and health consultant with Minneapolis-based Nutrition Concepts, say that diet and exercise regime changes can work over time if people keep them up and have realistic expectations.

The studies analysed varied in their weight-loss tactics, in some, participants were given only general advice on cutting pounds, while in others, they received exercise advice or actual help with boosting their physical activity levels, but no help with diet.

In trials that focused on diet, some emphasized calorie reduction alone, and some used a combination of diet and exercise; in some participants were given meal replacements or weight-loss medications such as orlistat (Xenical) to enhance their diet changes.

Overall the team found diet-focused trials were most successful and advice-only and exercise-only studies produced “minimal” weight loss.

It was found that in those which used calorie-cutting alone and in those that added exercise, weight loss typically hit a plateau after six months, and participants on average gained a few pounds back.

The researchers say people should be prepared for their weight loss to taper off and the goal should be maintaining whatever success has been achieved.

Franz and her colleagues found that weight-loss medication appeared to help retaining the weight loss over the longer-term.

Franz and her colleagues say dieters often become frustrated because they think that if they maintain the low-calorie habit, the pounds should continue to fall off, but this does not appear to happen even when weight-loss interventions are continued.

Experts say exercise is important for cardiovascular health and general health and fitness and the key factors in weight loss are restricting the diet and promoting exercise.

They say however that it takes a lot of exercise to burn off excess calories - an average-weight person will burn about 100 calories walking a mile - so reducing calories is important in attempting to lose weight.

The weight-loss equation comes down to calories in versus calories out and it takes a deficit of 3,500 calories to lose a pound of fat; to lose just 1 pound a week a person will need to create an average 500-calorie deficit each day.

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Orlistat - Xenical - The Main Product Marketed As Xenical

February 16, 2008 – 5:36 pm

While the dietary drug Orlistat continues to grab the headlines in this ground breaking treatment of obesity, many may not be aware that there are a number of variations of the treatment which are marketed under different names. Xenical is one such variation of the Orlistat drug, and a treatment which is proving ever more popular and ever more successful. How can you apply for Orlistat treatment?

As you can imagine for a treatment which promises to reduce body weight, without any serious side effects, there has been massive demand for Xenical. Unfortunately this has also spawned a number of illegal internet sites selling the drug, which is only available on prescription. Under no circumstance should you purchase any such treatments from the internet as usage needs to be monitored, and you do not know what you will receive when buying off the internet, with many reports of fake or potentially harmful tablets being delivered.

Your first port of call should be your doctor who will review your particular situation and decide whether Xenical may benefit you. This is done by taking your height and weight and calculating your Body Mass Index (BMI) which is a quick calculation to see if, and by how much, you are actually over weight. The treatment will only be prescribed for patients who are obese, and in need of a weight reduction program for health reasons.

It is also at this stage that your doctor will check your blood pressure, and an array of other possible health conditions which you may have, or may be present in your family chain. High blood pressure, diabetes, etc can often effect the final decision as to whether Xenical is the treatment for you.

How does Xenical actually work?

The difference between Xenical and many of the other weight loss drugs on the market is the fact that Xenical works by actually reducing the body’s intake of fatty components, rather than trying to supress your physical food intake.

The treatment works by reducing the production of lipase enzymes in your intestine which is where fatty content is converted into fatty acid and absorbed into your body - resulting in extra fat. By physically reducing the production of this enzyme the amount of fat absorbed into your body is immediately reduced by about 30%. Due to this reduced intake, your body has less calorific intake which when used in conjunction with an exercise plan will result in your body burning more fat and thereby further reducing your weight.

Any unprocessed fatty components of your digested food are immediately excreted out of the body by the usual channels.

Do you still need to exercise when taking Xenical?

While the treatment itself will have an immediate impact upon your BMI, the only way in which you will be able to retain the benefits is by also changing certain aspects of your lifestyle. You should really see Xenical as the first step in a more healthier lifestyle, not the final stage.

When visiting your doctor, they will only prescribe the treatment if you agree to increase your exercise routine, and also eat healthier, avoiding excessive intake of foods which have caused the initial weight gain. There needs to be a two tier approach, with Xenical giving the patient the initial boost of losing weight and the increased exercise and healthier living plan assisting with the long term goal of keeping the weight off.

Are there any side effects in taking Xenical?

While there are side effects when using Xenical, they are not serious and more of an uncomfortable nature unless certain precautions are taken. Due to the reduced absorption of fatty content, the excess fatty elements are excreted naturally. Initially stools can be loose and oily, with increased flatulence and some patients have reported experiencing sudden bowel movements in the early days.

However, these are side effects which can be negated by reducing the fatty content of your diet, which will have a direct impact upon the amount of fatty content passed through the body. Some users may also find it beneficial to take vitamin supplements until their body becomes used to the treatment.

Does Xenical really work?

As you would expect from a treatment which has the potential to change so many lives around the world, there have been extensive trials and research into the impact on an array of different patients. These results show that twice as many users of Xenical experienced weight loss of at least 10% in the first 12 months, against those on a traditional diet. Put in perspective, the results show that Xenical has the potential to not only have a major impact upon a patients weight, but also lead to a better all round standard of living.

The results of the various trials carried out over the last few years where presented to the American Food and Drugs Administration (FDA) who approved the treatment on prescription. However, they have also approved a variant of the treatment, Alli, for over the counter sale - the first time ever that an obesity treatment has been approved for over the counter use.

Summary

In summary, Xenical has the potential to change the lives of many obesity sufferers, with very little or no side effects to mention. The days when obesity treatments meant an operation, or a brain suppressant which reduced your food intake, have long gone. By physically reducing the amount of fat which is digested into the body, many will see an immediate impact from Xenical.

However, it must be stressed that in order for the treatment to have longer term implications, many patients will need to review their life styles and eating habits, instigating healthy changes on a long term basis. Light exercise is also a major part of the overall process, resulting in an increased feel good factor among many obesity sufferers.

Unfortunately obesity has become a major health issue over recent years, with many studies showing a marked increase in the weight of children from an early age. It is essential that the situation is addressed as soon as possible, in order to promote a more balanced approach to exercise and eating.

For many, the introduction of Xenical as a treatment will have a major impact on their health and their standard of living.

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Lose Weight Xenical

February 16, 2008 – 5:34 pm

Being overweight is not only a physical problem that gives birth to different diseases related to heart and other ailments like diabetes, high blood pressure, etc. but it also leads to severe mental problems like depression and inferiority complex, which makes a person impatient and irritated. Many overweight people tend to see themselves as losers and lack confidence while doing any work. People those who want to become a policeman; a defense personal or an airhostess should have a well-toned body. If you are an obese it is not possible for you to take-up any of the above-mentioned profession, no matter how much you like the profession and sincere towards it. The primary thing that you need to have to get into such profession is a fit body.

The Xenical effectively treats people those who are overweight or obese. This will reduce your fat and you will get back into shape within a course of few months. This medicine basically belongs to the group of Lipase Inhibitors. The Xenical doesn’t suppress your appetite rather it actually targets the absorption of the dietary fat that get into your body.

These dietary fats are large molecules, which need to be broken down before they can be absorbed by the body. Lipase is basically an enzyme that breaks them down. This is where lipases play an important role in the digestion of dietary fat. When taken with a meal, Xenical gets in the way of the activity of these enzymes and allows about 30% of the fat eaten in the meal to pass through the gut undigested. Therefore, your body cannot store these excess calories as fatty tissue or use them as a source of energy. This helps you to reduce your weight by burning up fat that you are already carrying, maintain your lower weight and reduce the chances of any weight regain.

It is suggested that you should have the Xenical Capsule with a well-balanced calorie controlled diet. Foods that are high on calorie and fat will continuously keep on increasing your weight because Xenical will keep only around 30% of the fat undigested. Exercising, while having the course of Xenical reduces weight very effectively and quickly.

It is always advisable that you consult your physician before you start having any sort of medicine, so it is the same in case of Xenical tablets. Consult your physician before you start the course of Xenical tablets and mention your diet and other details like if you are allergic to something or some pancreatic problem or if you had any recent major surgery to your stomach or intestine.

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December 12, 2007 – 10:10 pm

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Generic Xenical (ORLISTAT)  is a slimming tablet for those who are obese and who find it hard to lose weight although on a diet. If Xenical is used with a healthy diet and exercise it has shown to help patients lose weight. Xenical works by preventing fat from being digested, which in studies have shown to be very effective for people who, on a normal diet, have difficulties losing weight.

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Losing even small amounts of weight and keeping it off can have additional health benefits for you, especially if you are at risk of other diseases such as heart disease and diabetes. XENICAL can also help to improve risk factors associated with being overweight, such as high blood pressure, high cholesterol and high blood sugar. If these are not treated, they may lead to other diseases such as heart disease or diabetes.

In addition, Xenical-treated patients had statistically statistics reductions in some of the important chance factors that make fatness such a critical disease. These enclosed statistics reductions in multinomial and LDL cholesterol, systolic and diastolic vertebrate pressure, and showed improvements in vertebrate concentrations of dextrose and insulin.

Xenical acts by obstruction the benignity of lipases which normally disruption down triglyceride enabling acylglycerol to be attentive through the intestinal wall. Superabundance glyceride in the diet is a statesman antecedent of obesity. Xenical does not activity on the prosencephalon to stifle appetite, and does not enter the humor stream. In the objective studies, Xenical was well tolerated, and was not joint with any difficult cardiogram dockside effects.

Xenical has recently been recommended for espousal by the U.S. Vitellus and Abortifacient Administration’s Medicine and Zoology Drugs Informatory Politburo for yen referent care of fat person (BMI more than 30kg/m2) and in those with BMI more than 27kg/m2 who have chance factors. It is currently being reviewed by the Eudaimonia Shielding Stem of Upbeat Canada.

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December 12, 2007 – 9:55 pm

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How Xenical Works

Xenical blocks absorption of dietary fat into the bloodstream, thereby reducing the number of calories you get from a meal.

What is Xenical Weight Loss?

Xenical weight loss is nothing but the loss of weight with the help of the Food and drugs Administration (FDA) approved diet pill Xenical and Xenical mechanism is the primary factor that leads to effective weight loss with Xenical. For achieving weight loss with Xenical, the medicine is required to be taken strictly as per the guidelines dictated by the doctor and alongside other precautionary measures and safety procedures are also necessary.

At the usual dosage level, it cuts fat absorption by almost one-third. Combined with a low-calorie diet, it is used to promote weight loss and discourage the return of unwanted pounds.

The drug is prescribed for the frankly obese and for merely overweight people who have other health problems such as high blood pressure, diabetes, or high cholesterol levels. Your weight status is determined by your body mass index (BMI), a comparison of height to weight.

Directions
Take a capsule of Xenical during, or up to 1 hour after, each main meal. You should follow a nutritionally balanced, low-calorie diet that provides no more than 30 percent of its calories from fat. If you miss a meal, or the meal contains no fat, you can skip the accompanying dose of Xenical.

If you miss a dose… Resume taking Xenical at the next meal. Don”t try to make up the loss with a double dose. The extra drug won”t help.

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Orlistat Xenical

December 12, 2007 – 9:29 pm

What are Orlistat capsules?

Orlistat (Xenical) is used to help obese people lose weight and keep the weight off while eating a reduced-calorie diet. Orlistat decreases the amount of fat that is absorbed from your diet. Generic orlistat capsules are not yet available.

How should I take Orlistat Xenical?

Orlistat is taken by mouth and swallowed with a drink of liquid. Follow the directions on the prescription label. You can take orlistat with each main meal that contains about 30% of the calories from fat. Or you can take the capsule one hour after the meal. Do not take your medicine more often than directed. If you occasionally miss a meal or have a meal without fat, you can omit that dose of orlistat. Doses greater than 120 mg three times per day have not been shown to increase weight loss.

What should I watch for while taking Orlistat Xenical?

Watch for any unusual changes in your body’s normal function. You need to watch the amount of fat in your diet. Too much dietary fat can increase the side effects from orlistat. Also, watch for any changes in your eyesight, skin or hair that may be caused by a vitamin deficiency.

What side effects can Orlistats/Xenical cause?
The most common side effect of orlistat is changes in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of orlistat. Tell your doctor if any of these symptoms are severe or do not go away:

  • oily, spotting BMs
  • gas with discharge
  • urgent need to have a BM
  • oily or fatty stools
  • an oily discharge
  • increased number of BMs
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December 12, 2007 – 9:17 pm

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Xenical- Drug Uses

Xenical is used to help obese people who fit certain weight and height requirements lose weight and maintain weight loss. Xenical works in your intestines, where it blocks some of the fat you eat from being absorbed. This undigested fat is then eliminated in your bowel movements. Use Xenical together with a reduced-calorie diet. The weight management effects of Xenical continue only as long as you are taking it.

How Taken

If you order xenical you must know Xenical comes in a capsule to take it orally. It is usually taken tree times a day with food. Take Xenical exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Xenical should be given with meals. A diet consisting of daily intake of fat (30% of total calories), carbohydrates, and protein should be distributed evenly over 3 main meals.

There are also

Possible Side Effects with Xenical

Stop taking Xenical and seek emergency medical attention if you experience a rare allergic reaction including shortness of breath; closing of your throat; swelling of your lips, tongue, or face; or hives. Other, less serious side effects are more likely to occur. Continue to take Xenical and talk to your doctor if you experience oily spotting, gas with discharge, an urgent need to go to the bathroom, oily or fatty stools, an oily discharge, an increased number of bowel movements, an inability to control bowel movements, or orange or brown colored oil in your stool. The bowel changes listed above are a natural effect of blocking fat and indicate that Xenical is working. They generally occur early in treatment, particularly after meals containing higher amounts of fat than are recommended. These symptoms are usually temporary and lessen or disappear as you continue treatment and keep to your recommended diet of meals containing 30% fat. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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